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Ventilatory Response To Carbon Dioxide And To Oxygen After Acclimatization To Carbon Dioxide

Report Number: AMRL TDR 62-136
Author: Barnett, Thomas B.
Author: Peters, Richard M.
Corporate Author: Air Force Aerospace Medical Research Lab Wright-Patterson AFB OH
Laboratory: Biomedical Laboratory
Date of Publication: 1962-11
Pages: 18
Contract: AF 33(616)-6261
Project: 7163
Task: 716302
AD Number: AD0293993

A chawber has been designed so that dogs can be exposed for prolonged periods to abnormal atmospheres. The concentrations of CO2 and O2 are continuously controlled and recorded. Exposure of dogs to approximately 3 percent CO2 in air for 6 days or more resulted in a decrease in the ventilatory response to CO2. In control dogs the breathing of 50 per cent oxygen for 30 minutes was associated with a slight to moderate increase in ventilation without a significant change in arterial pCO2. After acclimatization to CO2 oxygen breathing was associated with Little change in ventilation but with a rise in arterial pCO2.

Lockheed Martin Missiles & Fire Control
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