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The goal of the Contrails project is to help preserve and disseminate the technical record of 20th century aerospace research, highlighting in particular the research endeavors of the Illinois Tech community.

Cutaneous Toxicity Evaluation of Air Force Development Materials - VI

Report Number: AMRL TDR 64-13
Author: Shelanski, Morris V.
Corporate Author: Industrial Biology Research and Testing Laboratories, Inc.
Laboratory: Biomedical Laboratory
Date of Publication: 1964-02
Pages: 15
Contract: AF 33(657)-8900
Project: 6302
Task: 630201
AD Number: AD0435776

Abstract:
Ten Air Force development materials were studied via the prophetic patch test method on laboratory animals to determine the primary irritant effect, gross sensitization index, and gross percutaneous toxicity of these materials. The patch test studies with rabbits indicated that three of the materials showed very mild primary irritant action. None of the materials produced any sensitization or gross systemic poisoning. Dermal reactions on rabbits were so mild that testing on humans was not precluded. The materials were, therefore, tested on human volunteers by the Shelanski repeated insult patch test. Results of this test indicated that all of the materials were safe to use on contact with human skin.


Provenance:
RAF Centre of Aviation Medicine
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